From Atoms to Medicine
by Ahmed H Zewail
This book brings about the confluence of various concepts and tools to
address significant problems of our time in physical biology and adjacent
The volume is structured to provide a broad perspective on current
state-of-the-art methods and concepts at the heart of chemical and biological
behavior, covering the topics of visualization, theory and computation for
complexity; macromolecular function, protein folding, and protein
misfolding; molecular recognition; and systems integration from cells to
The scope of tools is wide-ranging, spanning imaging, crystallography,
microfluidics, single-molecule spectroscopy, and synthetic probe targeting,
either molecular or by metallic particles.
Edited by Nobel Laureate Ahmed H Zewail, the book contains
contributions from other eminent scientists, of whom three are also Nobel
Prize winners. They include:
- David Baltimore — shared the 1975 Nobel Prize in Physiology or Medicine
for their discovery which provided the key to understanding the life cycle
Roger D Kornberg — Dr Kornberg won the 2006 Nobel Prize in Chemistry
(unshared). He discovered the nucleosome, the basic unit of DNA coiling
in chromosomes; and
Roderick MacKinnon — Dr MacKinnon is currently John D
Rockefeller Jr professor in the laboratory of Molecular Neurobiology
and Biophysics at Rockefeller University and Investigator of the Howard
Hughes Medical Institute. His research aims to understand the molecular
mechanisms of a class of integral membrane proteins known as ion
channels. He is the recipient of numerous scientific awards, including the
2003 Nobel Prize in Chemistry.
Nobel Laureate Ahmed H Zewail
Dr Ahmed H Zewail is the Linus Pauling Chair
Professor of Chemistry and Professor of Physics. For 10
years, he has been the director of the NSF Laboratory
for Molecular Sciences (LMS) at the California Institute
of Technology (Caltech). Currently, he is the director of
the Physical Biology Center at Caltech.
Dr Zewail was awarded the 1999 Nobel Prize for his development of the field
of femtochemistry, making possible discoveries of phenomena on the femtosecond
timescale. At present, the focus of his research group is mainly on the development of
four-dimensional microscopy for visualization in the four dimensions of space and time,
and the understanding of complexity of chemical and biological transformations.
Among the other honors he received are the Albert Einstein World Award (2006),
Benjamin Franklin Medal (1998), Robert A Welch Award (1997) Leonardo da Vinci
Award (1995), Wolf Prize (1993) and the King Faisal Prize (1989).
Dr Zewail serves on several boards of international institutions of higher learning.